Anti-beta-Amyloid (1-42) (1F4) Monoclonal, ALEXA Fluor 594

Catalog numberGENTObsm-0107M-A594
NameAnti-beta-Amyloid (1-42) (1F4) Monoclonal, ALEXA Fluor 594
Price€ 489.00
Size100 microliters
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TypeConjugated Primary Antibody
Conjugated withALEXA FLUOR 594
Host organismMouse (Mus musculus)
Target Protein/Peptidebeta-Amyloid 1-42
SpecificityHighly specific antibody against beta-Amyloid 1-42
ModificationNot modified
ClonalityMonoclonal Antibodies
Clone1F4
Concentration1ug per 1ul
Antigen SourceKLH conjugated synthetic peptide derived from human beta-Amyloid (1-42)
Gene ID351
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross Reactive speciesHuman (Homo sapiens), Rat (Rattus norvegicus)
Cross Reactive Species detailsNo significant cross reactivity is observed
Background informationThe cerebral and vascular plaques associated with Alzheimer's disease are mainly composed of Amyloid beta peptides. beta Amyloid is derived from cleavage of the Amyloid precursor protein and varies in length from 39 to 43 amino acids. beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides result from cleavage of Amyloid precursor protein after residues 40, 42, and 43, respectively. The cleavage takes place by gamma-secretase during the last Amyloid precursor protein processing step. beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides are major constituents of the plaques and tangles that occur in Alzheimer's disease. beta Amyloid and peptides have been developed as tools for elucidating the biology of Alzheimer's disease.
Purification methodPurified by Protein G.
StorageAqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Excitation emission590nm/617nm
Synonymsbeta-Amyloid
Alternative name 1beta-Amyloid (1-42) (1F4) Monoclonal Antibody, ALEXA FLUOR® 594 Conjugated
Alternative name 2beta-Amyloid (1-42) (1F4) Monoclonal anti-, ALEXA FLUOR 594 Conjugated
AdvisoryCycles of freezing and thawing should be avoided as such cycles may denature the peptide chains of the antibody and reduce its affinity, specificity and reactivity. For antibodies in a liquid form or reconstituted lyophilized antibodies - small amounts of the soultion could be captured on the cap or the walls of the container. Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom.
PropertiesFor facs or microscopy Alexa 1 conjugate.
ConjugationAlexa Fluor,ALEXA FLUOR® 594
ConjugatedAlexa conjugate 1
DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
AboutMonoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.