CLCA3 Antibody, ALEXA FLUOR 350

Catalog numberbs-13706R-A350
NameCLCA3 Antibody, ALEXA FLUOR 350
Price€ 380.00
Size100ul
  Get from shop
Long nameCLCA3 Polyclonal Antibody, ALEXA FLUOR 350 Conjugated
Also known asAnti-CLCA3 PAb ALEXA FLUOR 350
CategoryConjugated Primary Antibodies
Conjugated withALEXA FLUOR® 350
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCLCA3
SpecificityThis is a highly specific antibody against CLCA3.
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from mouse CLCA3
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
CrossreactivityMouse, Rat
Cross-reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the antigenThe calcium-activated chloride channel (CLCA) protein family, which includes the human homologs CLCA1 and CLCA2, display distinct tissue distribution patterns. CLCA1 is expressed as a precursor protein that is processed into two cell surface associated subunits and a group of proteins. CLCA1 is upregulated by interleukin-9 and regulates the expression of mucins. CLCA1 may provide a therapeutic target to control mucus overproduction in airway disease patients with cystic fibrosis. CLCA2 expression is downregulated in breast cancer, therefore CLCA2 is thought to act as a tumor suppressor in normal cells. CLCA3 (known as Clca3 in mouse) is a structurally divergent member of the CLCA family that does not function as a channel protein. CLCA4 is a CLCA member that is expressed in human rectal mucosa, CLCA5 shows strong expression in eye and spleen, and CLCA6 is primarily expressed in intestine and stomach.
PurificationPurified by Protein A.
Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Excitation emission343nm/442nm
SynonymsCalcium activated chloride channel 3; Calcium-activated chloride channel regulator family member 3; Chloride channel accessory 3 pseudogene; chloride channel calcium activated 3; Chloride channel calcium activated family member 3; Clca1; Clca2; CLCA3P; Gob 5; Gob-5; Gob5; hCLCA3; mCLCA3; MGC143984; MGC143985.
PropertiesFor facs or microscopy Alexa 1 conjugate.Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
ConjugationAlexa Fluor,ALEXA FLUOR 350
French translationanticorps