| Long name | SKAP55 Polyclonal Antibody, ALEXA FLUOR 647 Conjugated |
|---|
| Also known as | Anti-SKAP55 PAb ALEXA FLUOR 647 |
|---|
| Category | Conjugated Primary Antibodies |
|---|
| Conjugated with | ALEXA FLUOR® 647 |
|---|
| Host Organism | Rabbit (Oryctolagus cuniculus) |
|---|
| Target Antigen | SKAP55 |
|---|
| Specificity | This is a highly specific antibody against SKAP55. |
|---|
| Modification | Unmodified |
|---|
| Modification Site | None |
|---|
| Clonality | Polyclonal |
|---|
| Clone | Polyclonal antibody |
|---|
| Concentration | 1ug per 1ul |
|---|
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SKAP55 |
|---|
| Tested applications | IF(IHC-P) |
|---|
| Recommended dilutions | IF(IHC-P)(1:50-200) |
|---|
| Crossreactivity | Human, Rat |
|---|
| Cross-reactive species details | Due to limited amount of testing and knowledge, not every possible cross-reactivity is known. |
|---|
| Background of the antigen | Fyb (Fyn binding protein) and the anchoring proteins SKAP55 and SKAP55-R (SKAP55-related protein) associate with the tyrosine kinase p59fyn. SKAP55 and SKAP55-R bind to Fyb through their SH3 domains and function as substrates for p59Fyn in resting T cells. SKAP55 contains an N-terminal pleckstrin homology domain and a C-terminal SH3 domain binding motif of adjacent arginine and lysine residues followed by tandem tyrosines. SKAP55-R, similar in overall structure to SKAP55, contains a coiled-coil N-terminal domain. SKAP55 associates with SLAP-130, another component of the Fyn complex, which plays a role in the regulation of signaling events initiated by lymphocyte antigen receptors leading up to T cell activation. The human SKAP55 gene maps to chromosome 17q21.32 and encodes a 359 amino acid protein. |
|---|
| Purification | Purified by Protein A. |
|---|
| Storage conditions | Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year. |
|---|
| Excitation emission | 650nm/665nm |
|---|
| Synonyms | pp55; SCAP 1; SCAP1; SKAP 1; SKAP 55; SKAP-55; Skap1; SKAP1_HUMAN; SKAP55 adaptor protein; SRC family associated phosphoprotein 1; Src family-associated phosphoprotein 1; Src kinase associated phosphoprotein 1; SRC kinase associated phosphoprotein 55 kD; Src kinase associated phosphoprotein of 55 kDa; Src kinase-associated phosphoprotein 1; Src kinase-associated phosphoprotein of 55 kDa. |
|---|
| Properties | For facs or microscopy Alexa 1 conjugate.Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-SKAP55 exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. |
|---|
| Conjugation | Alexa Fluor,ALEXA FLUOR 647 |
|---|
| French translation | anticorps |
|---|