Long name | beta Catenin (Tyr489) Antibody, ALEXA FLUOR 350 Conjugated |
---|
Also known as | Anti-beta Catenin Tyr489 PAb ALEXA FLUOR 350 |
---|
Category | Conjugated Primary Antibodies |
---|
Conjugated with | ALEXA FLUOR® 350 |
---|
Host Organism | Rabbit (Oryctolagus cuniculus) |
---|
Target Antigen | beta Catenin Tyr489 |
---|
Specificity | This is a highly specific antibody against beta Catenin Tyr489. |
---|
Modification | Phosphorylation |
---|
Modification Site | Tyr489 |
---|
Clonality | Polyclonal |
---|
Clone | Polyclonal antibody |
---|
Concentration | 1ug per 1ul |
---|
Source | KLH conjugated synthetic phosphopeptide derived from human beta Catenin around the phosphorylation site of Tyr489 |
---|
Gene ID Number | 1499 |
---|
Tested applications | IF(IHC-P) |
---|
Recommended dilutions | IF(IHC-P)(1:50-200) |
---|
Crossreactivity | Human, Mouse, Rat |
---|
Cross-reactive species details | Due to limited amount of testing and knowledge, not every possible cross-reactivity is known. |
---|
Background of the antigen | The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Oct 2009]. |
---|
Purification | Purified by Protein A. |
---|
Storage conditions | Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year. |
---|
Excitation emission | 343nm/442nm |
---|
Synonyms | beta Catenin phospho Y489; beta Catenin phospho Tyr489; p-beta Catenin Y489; p-beta Catenin Tyr489; beta-catenin; beta catenin; CTNNB1; CHBCAT; CTNNB1; CTNNB; PRO2286; Cadherin associated protein; Catenin cadherin associated protein, beta 1, 88kDa; Catenin beta 1; Catenin beta-1; CATNB; CTNB1_HUMAN; CTNNB; CTNNB1; DKFZp686D02253; FLJ25606; FLJ37923; b-catenin; OTTHUMP00000162082; OTTHUMP00000165222; OTTHUMP00000165223; OTTHUMP00000209288; OTTHUMP00000209289. |
---|
Properties | For facs or microscopy Alexa 1 conjugate.Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. |
---|
Conjugation | Alexa Fluor,ALEXA FLUOR 350 |
---|
French translation | anticorps |
---|