Anti-beta Catenin Tyr489 | Technique alternative

Catalog number	bs-12857R-A350
Name	beta Catenin (Tyr489) Antibody, ALEXA FLUOR 350
Price	€ 350.15
Size	100ul
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Long name	beta Catenin (Tyr489) Antibody, ALEXA FLUOR 350 Conjugated
Also known as	Anti-beta Catenin Tyr489 PAb ALEXA FLUOR 350
Category	Conjugated Primary Antibodies
Conjugated with	ALEXA FLUOR® 350
Host Organism	Rabbit (Oryctolagus cuniculus)
Target Antigen	beta Catenin Tyr489
Specificity	This is a highly specific antibody against beta Catenin Tyr489.
Modification	Phosphorylation
Modification Site	Tyr489
Clonality	Polyclonal
Clone	Polyclonal antibody
Concentration	1ug per 1ul
Source	KLH conjugated synthetic phosphopeptide derived from human beta Catenin around the phosphorylation site of Tyr489
Gene ID Number	1499
Tested applications	IF(IHC-P)
Recommended dilutions	IF(IHC-P)(1:50-200)
Crossreactivity	Human, Mouse, Rat
Cross-reactive species details	Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the antigen	The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Oct 2009].
Purification	Purified by Protein A.
Storage conditions	Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Excitation emission	343nm/442nm
Synonyms	beta Catenin phospho Y489; beta Catenin phospho Tyr489; p-beta Catenin Y489; p-beta Catenin Tyr489; beta-catenin; beta catenin; CTNNB1; CHBCAT; CTNNB1; CTNNB; PRO2286; Cadherin associated protein; Catenin cadherin associated protein, beta 1, 88kDa; Catenin beta 1; Catenin beta-1; CATNB; CTNB1_HUMAN; CTNNB; CTNNB1; DKFZp686D02253; FLJ25606; FLJ37923; b-catenin; OTTHUMP00000162082; OTTHUMP00000165222; OTTHUMP00000165223; OTTHUMP00000209288; OTTHUMP00000209289.
Properties	For facs or microscopy Alexa 1 conjugate.Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Conjugation	Alexa Fluor,ALEXA FLUOR 350
French translation	anticorps

Long name

beta Catenin (Tyr489) Antibody, ALEXA FLUOR 350 Conjugated

Also known as

Anti-beta Catenin Tyr489 PAb ALEXA FLUOR 350

Category

Conjugated Primary Antibodies

Conjugated with

ALEXA FLUOR® 350

Host Organism

Rabbit (Oryctolagus cuniculus)

Target Antigen

beta Catenin Tyr489

Specificity

This is a highly specific antibody against beta Catenin Tyr489.

Modification

Phosphorylation

Modification Site

Tyr489

Clonality

Polyclonal

Clone

Polyclonal antibody

Concentration

1ug per 1ul

Source

KLH conjugated synthetic phosphopeptide derived from human beta Catenin around the phosphorylation site of Tyr489

Gene ID Number

1499

Tested applications

IF(IHC-P)

Recommended dilutions

IF(IHC-P)(1:50-200)

Crossreactivity

Human, Mouse, Rat

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Background of the antigen

The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Oct 2009].

Purification

Purified by Protein A.

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Excitation emission

343nm/442nm

Synonyms

beta Catenin phospho Y489; beta Catenin phospho Tyr489; p-beta Catenin Y489; p-beta Catenin Tyr489; beta-catenin; beta catenin; CTNNB1; CHBCAT; CTNNB1; CTNNB; PRO2286; Cadherin associated protein; Catenin cadherin associated protein, beta 1, 88kDa; Catenin beta 1; Catenin beta-1; CATNB; CTNB1_HUMAN; CTNNB; CTNNB1; DKFZp686D02253; FLJ25606; FLJ37923; b-catenin; OTTHUMP00000162082; OTTHUMP00000165222; OTTHUMP00000165223; OTTHUMP00000209288; OTTHUMP00000209289.

Properties

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Conjugation

Alexa Fluor,ALEXA FLUOR 350

French translation

anticorps