SEMA3E/Semaphorin 3E Antibody, ALEXA FLUOR 488

Catalog numberbs-11480R-A488
NameSEMA3E/Semaphorin 3E Antibody, ALEXA FLUOR 488
Price€ 380.00
Size100ul
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Long nameSEMA3E/Semaphorin 3E Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
Also known asAnti-SEMA3E/Semaphorin 3E PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated withALEXA FLUOR® 488
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSEMA3E/Semaphorin 3E
SpecificityThis is a highly specific antibody against SEMA3E/Semaphorin 3E.
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SEMA3E/Semaphorin 3E
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
CrossreactivityHuman, Mouse, Rat
Cross-reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the antigenSemaphorins are a family of cell surface and secreted proteins involved in neural development that are conserved from insects to humans. Members of this family are approximately 750 amino acids in length (including signal sequences) and are defined by a conserved extracellular “semaphorin” domain of approximately 500 amino acids containing 14-16 cysteines, blocks of conserved sequences and no obvious repeats. The transmembrane semaphorins are characterized by an additional 80 amino acid transmembrane domain and an 80-110 amino acid cytoplasmic domain. Secreted and cell-bound semaphorins chemically attract and repel the growth of neural axons, guiding the development of intricate networks of neural tissue. SEMA3E is a secreted semaphorin with 775 amino acids. Mutations in the SEMA3E gene are associated with CHARGE syndrome, a disorder characterized by cranial nerve dysfunction, coloboma of the eye, choanal atresia, inner and external ear abnormalities, cardiac anomalies, genitourinary abnormalities, and growth retardation.
PurificationPurified by Protein A.
Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Excitation emission499nm/519nm
SynonymsColl 5; Coll5; KIAA0331; M sema H; M SEMAH; M SemaK; Msema H; MSEMAH; MSemaK; SEM3E_HUMAN; Sema domain immunoglobulin domain Ig; Sema domain immunoglobulin domain Ig short basic domain secreted 3E; Sema domain, immunoglobulin domain Ig, short basic domain, secreted, semaphorin 3E; SEMA3E; SEMAH; Semaphorin 3E; Semaphorin-3E; Semaphorin3E; Short basic domain secreted semaphorin 3E; SEM3E_HUMAN.
PropertiesFor facs or microscopy Alexa 1 conjugate.Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-SEMA3E/Semaphorin 3E has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
ConjugationAlexa Fluor
French translationanticorps