| Long name | KIBRA Polyclonal Antibody, ALEXA FLUOR 594 Conjugated |
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| Also known as | Anti-KIBRA PAb ALEXA FLUOR 594 |
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| Category | Conjugated Primary Antibodies |
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| Conjugated with | ALEXA FLUOR® 594 |
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| Host Organism | Rabbit (Oryctolagus cuniculus) |
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| Target Antigen | KIBRA |
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| Specificity | This is a highly specific antibody against KIBRA. |
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| Modification | Unmodified |
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| Modification Site | None |
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| Clonality | Polyclonal |
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| Clone | Polyclonal antibody |
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| Concentration | 1ug per 1ul |
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| Immunogen range | 370-420/1113 |
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| Subcellular location | Cytoplasm, Nucleus |
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| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human KIBRA |
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| Gene ID Number | 23286 |
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| Swiss Prot | Q8IX03 |
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| Tested applications | IF(IHC-P) |
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| Recommended dilutions | IF(IHC-P)(1:50-200) |
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| Crossreactivity | Human, Mouse, Rat |
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| Cross-reactive species details | Due to limited amount of testing and knowledge, not every possible cross-reactivity is known. |
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| Background of the antigen | Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with NF2 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. Acts as a transcriptional coactivator of ESR1 which plays an essential role in DYNLL1-mediated ESR1 transactivation. Regulates collagen-stimulated activation of the ERK/MAPK cascade. Modulates directional migration of podocytes. Acts as a substrate for PRKCZ. Plays a role in cognition and memory performance. |
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| Purification | Purified by Protein A. |
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| Storage conditions | Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year. |
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| Excitation emission | 590nm/617nm |
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| Synonyms | KIBRA; HBEBP3; HBEBP36; MEMRYQTL; PPP1R168; Protein KIBRA; HBeAg-binding protein 3; Kidney and brain protein; WW domain-containing protein 1; WWC1; KIAA0869 |
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| Properties | For facs or microscopy Alexa 1 conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. |
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| Conjugation | Alexa Fluor,ALEXA FLUOR® 594 |
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| Conjugated | Alexa conjugate 1 |
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| French translation | anticorps |
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