PDE4D Antibody, ALEXA FLUOR 555

Catalog numberbs-1325R-A555
NamePDE4D Antibody, ALEXA FLUOR 555
Price€ 380.00
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Long namePDE4D Polyclonal Antibody, ALEXA FLUOR 555 Conjugated
Also known asAnti-PDE4D PAb ALEXA FLUOR 555
CategoryConjugated Primary Antibodies
Conjugated withALEXA FLUOR® 555
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPDE4D
SpecificityThis is a highly specific antibody against PDE4D.
Modification SiteNone
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PDE4D
Gene ID Number5144
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
CrossreactivityHuman, Mouse, Rat
Cross-reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the antigenCyclic AMP-dependent phosphodiesterase type D (PDE4D) family is comprise of 5 variants (PDE4D1, D2, D3, D4 and D5). One or more PDE4D subtype variants are ubiquitously present in all mammalian cells. In CNS all five PDE4D subtype variants are expressed in varying ratios and their activity is regulated in tandem with GPCRs stimulation. Peripheral tissues also exhibit differential expression of PDE4D variants. PDE4D1/D2 mRNA levels rise in response to an increase in cAMP. Short term regulation of PDE4D variants involved PKA, MAP kinases and Erk2 phosphorylation that results in rapid change in their enzymatic activities. Other regulatory mechanism involved protein protein interactions with cytoskeletal scaffolding proteins.
PurificationPurified by Protein A.
Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Excitation emission553nm/568nm
SynonymscAMP specic 3',5' cyclic phosphodiesterase 4D; DKFZp686M11213; FLJ97311; cAMP specic 3' 5' cyclic phosphodiesterase 4D; cAMP specic phosphodiesterase 4D; cAMP specic phosphodiesterase PDE4D; cAMP specic phosphodiesterase PDE4D6; cyclic AMP phosphodiesterase; DPDE 3; DPDE3; Dunce like phosphodiesterase E3; HSPDE4D; PDE 43; PDE43; PDE4DN2; Phosphodiesterase 4D cAMP specic dunce Drosophila homolog phosphodiesterase E3; Phosphodiesterase 4D cAMP specic phosphodiesterase E3 dunce homolog Drosophila; Phosphodiesterase 4D cAMP specic; Phosphodiesterase 4D, cAMP specic dunce; Phosphodiesterase E3 dunce homolog Drosophila; STRK 1; STRK1.
PropertiesFor facs or microscopy Alexa 1 conjugate.Very high photo stable ALEXA conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
ConjugationAlexa Fluor,ALEXA FLUOR 555
French translationanticorps