CRP (C11F2) Monoclonal Antibody, ALEXA FLUOR 647

Catalog numberbsm-0391M-A647
NameCRP (C11F2) Monoclonal Antibody, ALEXA FLUOR 647
Price€ 380.00
Size100ul
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Long nameCRP (C11F2) Monoclonal Antibody, ALEXA FLUOR 647 Conjugated
Also known asAnti-CRPC MAb ALEXA FLUOR 647
CategoryConjugated Primary Antibodies
Conjugated withALEXA FLUOR® 647
Host OrganismMouse (Mus musculus)
Target AntigenCRPC
SpecificityThis is a highly specific antibody against CRPC.
ModificationUnmodified
Modification SiteNone
ClonalityMonoclonal
CloneC11F2
Concentration1ug per 1ul
Subcellular locationSecreted
SourceRecombinant CRP protein
Gene ID Number1401
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
CrossreactivityHuman
Cross-reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the antigenC Reactive Protein is a major acute phase reactant synthesized primarily in the liver hepatocytes. It is a pentraxin (cyclic pentameric protein) compound of five identical nonglycosylated subunits of 206 amino acids each (m.w. 24 kDa), that are bound noncovalently to form the physiologic CRP molecule (m.w. 117.5 kDa). C Reactive Protein mediates activities associated with preimmune nonspecific host resistance. It is opsonic, an initiator of the classical complement cascade and an activator of monocytes/macrophages. CRP also binds to several nuclear components including chromatin, histones and snRNP, suggesting that it may play a role as a scavenger during cell necrosis. Studies have revealed that among other markers of inflammation, CRP shows the strongest association with cardiovascular events. Many clinical studies demonstrated that coronary mortality among patients with unstable angina and elevated CRP is significantly higher comparing with the patients without elevated CRP. Measurements of C reactive protein (hsCRP) in the patients with ischemic heart disease provide a novel method for detecting individuals at high risk of plaque rupture.
PurificationPurified by Protein G.
Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Excitation emission650nm/665nm
SynonymsC reactive protein pentraxin related; CRP; MGC88244; PTX 1; PTX1; C Reactive Protein.
PropertiesFor facs or microscopy Alexa 1 conjugate.Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-CRPC exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
ConjugationAlexa Fluor,ALEXA FLUOR 647
GeneC reactive proteins are detected by anti-CRP antibodies supplied by GENTAUR.
AboutMonoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
French translationanticorps