Bax Antibody, ALEXA FLUOR 488

Catalog numberbs-0127R-A488
NameBax Antibody, ALEXA FLUOR 488
Price€ 380.00
Size100ul
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Long nameBax Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
Also known asAnti-Bax PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated withALEXA FLUOR® 488
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenBax
SpecificityThis is a highly specific antibody against Bax.
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range60-110/192
Subcellular locationMitochondrion
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Bax
Gene ID Number581
Swiss ProtQ07812
Tested applicationsFCM, IF(IHC-P), IF(ICC)
Recommended dilutionsFCM(1:20-100), IF(IHC-P)(1:50-200), IF(ICC)(1:50-200)
CrossreactivityHuman, Mouse, Rat, Pig, Rabbit
Cross-reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the antigenAccelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
PurificationPurified by Protein A.
Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Excitation emission499nm/519nm
SynonymsBCL2L4; Apoptosis regulator BAX; Bcl-2-like protein 4; Bcl2-L-4; BAX
PropertiesFor facs or microscopy Alexa 1 conjugate.Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-Bax has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
ConjugationAlexa Fluor
French translationanticorps