Acetyl Coenzyme A Carboxylase alpha (Ser1263) Antibody, ALEXA FLUOR 555

Catalog numberbs-12955R-A555
NameAcetyl Coenzyme A Carboxylase alpha (Ser1263) Antibody, ALEXA FLUOR 555
Price€ 350.15
Size100ul
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Long nameAcetyl Coenzyme A Carboxylase alpha (Ser1263) Antibody, ALEXA FLUOR 555 Conjugated
Also known asAnti-Acetyl Coenzyme A Carboxylase alpha Ser1263 PAb ALEXA FLUOR 555
CategoryConjugated Primary Antibodies
Conjugated withALEXA FLUOR® 555
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenAcetyl Coenzyme A Carboxylase alpha Ser1263
SpecificityThis is a highly specific antibody against Acetyl Coenzyme A Carboxylase alpha Ser1263.
ModificationPhosphorylation
Modification SiteSer1263
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human Acetyl Coenzyme A Carboxylase alpha around the phosphorylation site of Ser1263
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
CrossreactivityHuman
Cross-reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the antigenAcetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
PurificationPurified by Protein A.
Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Excitation emission553nm/568nm
SynonymsAcetyl Coenzyme A Carboxylase alpha phospho S1263; p-Acetyl Coenzyme A Carboxylase alpha phospho S1263; ACAC; ACACA; ACACA; ACACA_HUMAN; ACC alpha; ACC; ACC-alpha; ACC1; ACC1; ACCA; acetyl CoA carboxylase 1; acetyl Coenzyme A; Acetyl Coenzyme A; Biotin carboxylase; Acetyl-Coenzyme A Carboxylase alpha.
DescriptionN terminal acetylation or CH3CO as epigenetic regulation of Anti-Acetyl Coenzyme A Carboxylase alpha Ser1263 by NATs.The Anti-Acetyl Coenzyme A Carboxylase alpha Ser1263 is a α- or alpha protein sometimes glycoprotein present in blood.
PropertiesFor facs or microscopy Alexa 1 conjugate.Very high photo stable ALEXA conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
ConjugationAlexa Fluor,ALEXA FLUOR 555
French translationanticorps