Hepatitis B virus X protein Antibody, ALEXA FLUOR 350

Catalog numberbs-2147R-A350
NameHepatitis B virus X protein Antibody, ALEXA FLUOR 350
Price€ 380.00
Size100ul
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Long nameHepatitis B virus X protein Antibody, ALEXA FLUOR 350 Conjugated
Also known asAnti-Hepatitis B virus X protein PAb ALEXA FLUOR 350
CategoryConjugated Primary Antibodies
Conjugated withALEXA FLUOR® 350
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenHepatitis B virus X protein
SpecificityThis is a highly specific antibody against Hepatitis B virus X protein.
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range10-60/210
SourceKLH conjugated synthetic peptide derived from Hepatitis B virus X protein
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
CrossreactivityVirus
Cross-reactive species detailsHepatitis B virus
Background of the antigenMultifunctional protein that may modulate protein degradation pathways, apoptosis, transcription, signal transduction, cell cycle progress, and genetic stability by directly or indirectly interacting with hosts factors. Does not seem to be essential for HBV infection. May be directly involved in development of cirrhosis and liver cancer (hepatocellular carcinoma). Most of cytosolic activities involve modulation of cytosolic calcium. The effect on apoptosis is controversial depending on the cell types in which the studies have been conducted. By binding to human DDB1, may affect cell viability and stimulate genome replication. May induce apoptosis by localizing in mitochondria and causing loss of mitochondrial membrane potential. May also modulate apoptosis by binding human CFLAR, a key regulator of the death-inducing signaling complex (DISC). Moderately stimulates transcription of many different viral and cellular transcription elements. Promoters and enhancers stimulated by HBx contain DNA binding sites for NF-kappa-B, AP-1, AP-2, c-EBP, ATF/CREB, or the calcium-activated factor NF-AT. May bind bZIP transcription factors like CREB1 (By similarity).
PurificationPurified by Protein A.
Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Excitation emission343nm/442nm
SynonymsHBX; pre-X protein; HB-X; X protein; HBV X protein; X protein [Hepatitis B virus].
Virushepatitis
PropertiesFor facs or microscopy Alexa 1 conjugate.Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
ConjugationAlexa Fluor,ALEXA FLUOR 350
DescriptionHepatitis a, b, c, d, e recombinant surface viral antigens to genotype 1, 2, 3, 4, 5 are used for antibody production to make diagnostic poly or monoclonal antibodies. Hepatitis is a disease of the liver characterized by the presence of inflammatory cells in the tissue of the organ. Hepatitis may occur without symptoms, but can lead to jaundice (a yellow discoloration of the skin, mucous membranes, and conjunctiva of the eyes), poor appetite, and fatigue. Depending on the cause, hepatitis can manifest either as an acute or as a chronic disease.
French translationanticorps