LAT (Tyr161) Antibody, ALEXA FLUOR 647

Catalog numberbs-10127R-A647
NameLAT (Tyr161) Antibody, ALEXA FLUOR 647
Price€ 350.15
Size100ul
  Get from shop
Long nameLAT (Tyr161) Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
Also known asAnti-LAT Tyr161 PAb ALEXA FLUOR 647
CategoryConjugated Primary Antibodies
Conjugated withALEXA FLUOR® 647
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenLAT Tyr161
SpecificityThis is a highly specific antibody against LAT Tyr161.
ModificationPhosphorylation
Modification SiteTyr161
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range145-195/262
Subcellular locationCytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human LAT around the phosphorylation site of Tyr161
Gene ID Number27040
Swiss ProtO43561
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
CrossreactivityHuman, Mouse, Rat
Cross-reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the antigenRequired for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules.
PurificationPurified by Protein A.
Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Excitation emission650nm/665nm
SynonymsLAT1; pp36; Linker for activation of T-cells family member 1; 36 kDa phospho-tyrosine adapter protein; p36-38; LAT
PropertiesFor facs or microscopy Alexa 1 conjugate.Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-LAT Tyr161 exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
ConjugationAlexa Fluor,ALEXA FLUOR 647
French translationanticorps