PLC beta3 (Ser537) Antibody, ALEXA FLUOR 594

Catalog numberbs-3340R-A594
NamePLC beta3 (Ser537) Antibody, ALEXA FLUOR 594
Price€ 350.15
Size100ul
  Get from shop
Long namePLC beta3 (Ser537) Polyclonal Antibody, ALEXA FLUOR 594 Conjugated
Also known asAnti-PLC beta3 Ser537 PAb ALEXA FLUOR 594
CategoryConjugated Primary Antibodies
Conjugated withALEXA FLUOR® 594
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPLC beta3 Ser537
SpecificityThis is a highly specific antibody against PLC beta3 Ser537.
ModificationPhosphorylation
Modification SiteSer537
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human PLC beta3 around the phosphorylation site of Ser537
Gene ID Number5331
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
CrossreactivityHuman, Mouse, Rat
Cross-reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the antigenThe protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene.
PurificationPurified by Protein A.
Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Excitation emission590nm/617nm
SynonymsPLC beta3 Ser537; Phospholipase C beta 3; Phospholipase C beta 3 phosphatidylinositol specic; PLC beta 3; PLCB3 antibody 1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase beta 3; Phosphoinositide phospholipase C; PLCB3_HUMAN.
PropertiesFor facs or microscopy Alexa 1 conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
ConjugationAlexa Fluor,ALEXA FLUOR® 594
ConjugatedAlexa conjugate 1
French translationanticorps