STAT3 (Ser727) Antibody, ALEXA FLUOR 647

Catalog numberbs-3429R-A647
NameSTAT3 (Ser727) Antibody, ALEXA FLUOR 647
Price€ 350.15
Size100ul
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Long nameSTAT3 (Ser727) Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
Also known asAnti-STAT3 Ser727 PAb ALEXA FLUOR 647
CategoryConjugated Primary Antibodies
Conjugated withALEXA FLUOR® 647
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSTAT3 Ser727
SpecificityThis is a highly specific antibody against STAT3 Ser727.
ModificationPhosphorylation
Modification SiteSer727
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range710-740/770
Subcellular locationCytoplasm, Nucleus
SourceKLH conjugated synthetic phosphopeptide derived from human STAT3 around the phosphorylation site of Ser727
Gene ID Number6774
Swiss ProtP40763
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
CrossreactivityHuman, Mouse, Rat
Cross-reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the antigenSignal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G (By similarity).
PurificationPurified by Protein A.
Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Excitation emission650nm/665nm
SynonymsAPRF; HIES; ADMIO; Signal transducer and activator of transcription 3; Acute-phase response factor; STAT3
PropertiesFor facs or microscopy Alexa 1 conjugate.Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-STAT3 Ser727 exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
ConjugationAlexa Fluor,ALEXA FLUOR 647
French translationanticorps