CARD4 Antibody

Catalog numberbs-7085R
NameCARD4 Antibody
Price€ 263.00
Size0.1ml
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Long nameCARD4 Primary Polyclonal Antibody
Also known asCARD4 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCARD4
SpecificityThis is a highly specific antibody against CARD4.
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range64-105/953
Subcellular locationHelical
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CARD4
Gene ID number10392
Swiss ProtQ9Y239
Tested ApplicationsWB, IHC-P, IF(IHC-P)
Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Cross reactivityHuman, Mouse, Rat
Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the target antigenEnhances caspase-9-mediated apoptosis. Induces NF-kappa-B activity via RIPK2 and IKK-gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS). Forms an intracellular sensing system along with ARHGEF2 for the detection of microbial effectors during cell invasion by pathogens. Required for RHOA and RIPK2 dependent NF-kappa-B signaling pathway activation upon S.flexneri cell invasion. Involved not only in sensing peptidoglycan (PGN)-derived muropeptides but also in the activation of NF-kappa-B by Shigella effector proteins IpgB2 and OspB. Recruits NLRP10 to the cell membrane following bacterial infection.
Purification methodThis antibody was purified via Protein A.
Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
Synonym namesCARD4; NLRC1; CLR7.1; Nucleotide-binding oligomerization domain-containing protein 1; Caspase recruitment domain-containing protein 4; NOD1
PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translationanticorps