Nicastrin Antibody

Catalog numberbs-6058R
NameNicastrin Antibody
Price€ 263.00
Size0.1ml
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Long nameNicastrin Primary Polyclonal Antibody
Also known asNicastrin PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenNicastrin
SpecificityThis is a highly specific antibody against Nicastrin.
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range33-83/709
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Nicastrin
Gene ID number23385
Swiss ProtQ92542
Tested ApplicationsWB, IHC-P, IF(IHC-P)
Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Cross reactivityHuman, Mouse, Rat
Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the target antigenEssential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex.
Purification methodThis antibody was purified via Protein A.
Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
Synonym namesATAG1874; Nicastrin; NCSTN; KIAA0253; UNQ1874/PRO4317
PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translationanticorps